KMID : 0358420170600010124
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Korean Journal of Obstetrics and Gynecology 2017 Volume.60 No. 1 p.124 ~ p.128
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Extrauterine epithelioid trophoblastic tumor in hysterectomized woman
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Kim Ji-Hye
Lee Sun-Kyung Hwang Soo-Hyun Kim Jung-Sun Yoon Gun Lee Yoo-Young Kim Tae-Joong Choi Chel-Hun Kim Byoung-Gie Bae Duk-Soo Lee Jeong-Won
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Abstract
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Epithelioid trophoblastic tumor (ETT) is a very rare variant of gestational trophoblastic disease (GTD) which arises in reproductive age women with prior gestational history. Although abnormal vaginal bleeding is the most common symptom of ETT, there are no reported pathognomonic symptoms of ETT because of its rarity. ETT is similar to placental site trophoblastic tumor in terms of its slow growing characteristic and microscopic findings. Therefore, it could be misdiagnosed as placental site trophoblastic tumor or other types of GTD. Unlike other types of GTD, primary treatment of ETT is surgical resection because of its chemo-resistant nature. Accordingly, immunohistochemical staining is essential for accurate diagnosis and appropriate treatment. Here, we report a case of a 42-year-old hysterectomized woman with pelvic masses who suffered from abdominal pain. Through laparotomy, tumors were resected completely and they were diagnosed as ETT through immunohistochemical stain. This report provides more evidence about its clinical features, diagnosis, and treatment including a brief review of the literature.
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KEYWORD
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Beta human chorionic gonadotropin, Epithelioid trophoblastic tumor, Gestational trophoblastic disease
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