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KMID : 0358420170600010124
Korean Journal of Obstetrics and Gynecology
2017 Volume.60 No. 1 p.124 ~ p.128
Extrauterine epithelioid trophoblastic tumor in hysterectomized woman
Kim Ji-Hye

Lee Sun-Kyung
Hwang Soo-Hyun
Kim Jung-Sun
Yoon Gun
Lee Yoo-Young
Kim Tae-Joong
Choi Chel-Hun
Kim Byoung-Gie
Bae Duk-Soo
Lee Jeong-Won
Abstract
Epithelioid trophoblastic tumor (ETT) is a very rare variant of gestational trophoblastic disease (GTD) which arises in reproductive age women with prior gestational history. Although abnormal vaginal bleeding is the most common symptom of ETT, there are no reported pathognomonic symptoms of ETT because of its rarity. ETT is similar to placental site trophoblastic tumor in terms of its slow growing characteristic and microscopic findings. Therefore, it could be misdiagnosed as placental site trophoblastic tumor or other types of GTD. Unlike other types of GTD, primary treatment of ETT is surgical resection because of its chemo-resistant nature. Accordingly, immunohistochemical staining is essential for accurate diagnosis and appropriate treatment. Here, we report a case of a 42-year-old hysterectomized woman with pelvic masses who suffered from abdominal pain. Through laparotomy, tumors were resected completely and they were diagnosed as ETT through immunohistochemical stain. This report provides more evidence about its clinical features, diagnosis, and treatment including a brief review of the literature.
KEYWORD
Beta human chorionic gonadotropin, Epithelioid trophoblastic tumor, Gestational trophoblastic disease
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